The Phosphatases
نویسندگان
چکیده
منابع مشابه
Phosphatases of the Liver
Because the liver carries out such a large number of important syntheses, it seems very.desirable to study the synthetic processes of this organ in vitro. However, there is considerable uncertainty in such studies because of the “notorious liver phosphatases,” which presumably could interfere with syntheses by breaking down ATP’ or any phosphorylated intermediates. In order to ascertain, if pos...
متن کاملThe Phosphatases of Human Erythrocytes
By HELEN QUINCY WOODARD, PH.D. V ARIOUS investigatorst5 have reported that erythrocytes exhibit phosphatase activity at pH values between 4 and 6, and some believe that this is due to two acid phosphatases with maximum activities at about pH 4.2. and .6. Reports on alkaline phosphatase activity have been less numerous.’ ‘ 6 , 7 In the course of an investigation of the glycerophosphatase activit...
متن کاملProtein Phosphatases Targeted Library
Preamble Phosphatases constitute a wide class of enzymes which remove a phosphate group from the target substrate by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl group. This action is directly opposite to that of phosphorylases and kinases. While kinases phosphorylate cellular substrates by using energetic molecules like ATP, phosphatases, in t...
متن کاملMetaplastic protein phosphatases.
Activity-dependent synaptic plasticity is widely considered to be one of the cellular mechanisms that underlie learning and memory. Long-term potentiation (LTP) is the most intensely studied form of synaptic plasticity, in part because it can be induced at glutamatergic synapses in the mammalian brain, including the hippocampus, a structure known for its involvement in memory function. LTP can ...
متن کاملPhosphotyrosyl protein phosphatases.
Enzyme-catalysed reversible protein phosphorylation is an important cellular regulatory mechanism (Nimmo & Cohen, 1977; Krebs & Beavo, 1979). Regulatory protein phosphorylation occurs most frequently on seryl and threonyl residues (Taborsky, 1974), and less frequently, on tyrosyl residues (Hunter, 1982). Protein phosphotyrosine [Tyr(P)] normally accounts for only 0.01-0.050o of the total protei...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1951
ISSN: 0032-5473
DOI: 10.1136/pgmj.27.304.64